Research Papers

Kurome Therapeutics Announces FDA Clearance of Investigational New Drug (IND) Application for KME-0584 for the Treatment of Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS)

Research Papers / aisoftware

Kurome Therapeutics Announces FDA Clearance of Investigational New Drug (IND) Application for KME-0584 for the Treatment of Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS) Read More »

Double trouble: IRAK1/4 inhibitors in AML/MDS

Research Papers / aisoftware

Double trouble: IRAK1/4 inhibitors in AML/MDS Read More »

Paralog-Specific Signaling By IRAK1/4 Maintains MyD88-Independent Functions In MDS/AML

Research Papers / Caleb Conlin

Paralog-Specific Signaling By IRAK1/4 Maintains MyD88-Independent Functions In MDS/AML Read More »

Activation Of Targetable Inflammatory Immune Signaling Is Seen In Myelodysplastic Syndromes With SF3B1 Mutations

Research Papers / Caleb Conlin

Activation Of Targetable Inflammatory Immune Signaling Is Seen In Myelodysplastic Syndromes With SF3B1 Mutations Read More »

Innate Immune Pathways And Inflammation In Hematopoietic Aging, Clonal Hematopoiesis, And MDS

Research Papers / Caleb Conlin

Innate Immune Pathways And Inflammation In Hematopoietic Aging, Clonal Hematopoiesis, And MDS Read More »

IRAK1 And IRAK4 As Emerging Therapeutic Targets In Hematologic Malignancies

Research Papers / Caleb Conlin

IRAK1 And IRAK4 As Emerging Therapeutic Targets In Hematologic Malignancies Read More »

Sequential CRISPR Gene Editing In Human IPSCs Charts The Clonal Evolution Of Myeloid Leukemia And Identifies Early Disease Targets

Research Papers / Caleb Conlin

Sequential CRISPR Gene Editing In Human IPSCs Charts The Clonal Evolution Of Myeloid Leukemia And Identifies Early Disease Targets Read More »

Targeting AML-Associated FLT3 Mutations With A Type I Kinase Inhibitor

Research Papers / Caleb Conlin

Targeting AML-Associated FLT3 Mutations With A Type I Kinase Inhibitor Read More »

Overcoming Adaptive Therapy Resistance In AML By Targeting Immune Response Pathways

Research Papers / Caleb Conlin

Overcoming Adaptive Therapy Resistance In AML By Targeting Immune Response Pathways Read More »

U2AF1 Mutations Induce Oncogenic IRAK4 Isoforms And Activate Innate Immune Pathways In Myeloid Malignancies.

Research Papers / Caleb Conlin

U2AF1 Mutations Induce Oncogenic IRAK4 Isoforms And Activate Innate Immune Pathways In Myeloid Malignancies. Read More »